张美祥

一、个人简介

张美祥，教授，博士生导师。星空体育副院长。围绕植物与微生物互作，主要开展以下几个方面的星空体育研究：1）植物抗病机理及抗病基因工程；2）病原菌致病成灾机理与控制；3）生防菌剂和植物免疫诱抗剂的研发与应用。星空体育研究成果以第一或通讯作者发表在Cell Host & Microbe、Molecular Plant、Plant Physiology、Plant Journal、Plant Communications等国际期刊上。担任BMC Plant Biology编委，New Crops、Crop Health、《星空体育研究》和《星空体育》青年编委，Frontiers in Plant Science期刊客座编委。Current Biology、Trends in Plant Science、New Phytologist、PLoS Pathogens、Plant Physiology、Plant Journal、Plant Biotechnology Journal、Journal of Integrative Plant Biology等期刊审稿人。主持国家自然科学基金4项。

教育经历

2007.9-2012.7，西北农林科技大学，理学博士，导师：单卫星教授

2005.9-2007.7，西北农林科技大学，理学硕士，导师：郭蔼光教授

2001.9-2005.7，西北农林科技大学，工学学士，导师：范三红副教授

工作经历

2021.7-至今，星空体育星空体育官方网站，教授

2015.12-2021.6，南京农业大学，副教授

2016.1-2018.7，美国加州大学戴维斯分校，博士后，导师：Gitta Coaker教授

2012.7-2015.12，南京农业大学，讲师

二、承担的科研项目

1. 国家自然科学基金面上项目，识别青枯菌Ⅲ型效应子RipP1的植物抗病蛋白鉴定及机制解析，32372483，2024.01-2027.12，主持

2. 国家自然科学基金面上项目，蛋白激酶RPC在番茄与辣椒疫霉互作中的作用和机理，32072399，2021.1-2024.12，主持

3. 国家自然科学基金面上项目，辣椒疫霉RXLR效应子操控植物NPR1蛋白抑制水杨酸抗病信号途径的分子机制解析，31672008，2017.01-2020.12，主持

4. 国家自然科学基金青年基金，大豆疫霉菌胞内效应因子CRN63的毒性作用机制，31301613，2014.01-2016.12，主持

5. 中央高校基本科研业务费优秀青年创新团队项目，2022.01-2024.12，主持

6. 星空体育星空体育官方网站引进人才科研启动经费，2021.7-2024.7，主持

7. 江苏高校“青蓝工程” 优秀青年骨干教师，2020-2023，主持

三、出版的著作

1.《星空体育概论数字课程》，2021，高等教育出版社，参编

2.《星空体育》，2020，科学出版社，参编

四、代表性论文

1. Jinfeng Peng, Liyuan Zhang, Kai Lu, Xiaochen Chen, Hao Pang, Xiaohui Yao, Ping Li, Peng Cao, Xiaoxu Li, Zuodong Wang, Lina Qin, Miao Zhou, Maoling Wang, Qizhen Li, Chunyu Qiu, Mingxi Sun, Yufen Li, Liping Gong, Xinlin Wei, Siyi Wang, Jiajia Chen, Chongchong Lu, Shenshen Zou, Xinhua Ding, Lei Chen*, Meixiang Zhang*, Hansong Dong*. Plant PI4P is required for bacteria to translocate type-3 effectors. New Phytologist. 2024. Accepted.

2. Jingwei Lu, Peng Cao, Shuangxi Zhang, Qinhu Wang, Zhiliang Xiao, He Meng, Zhimao Sun, Bixin Bai, Lirui Cheng, Aiguo Yang, Yuyan An*, Meixiang Zhang*. RIN4 immunity regulators mediate recognition of the core effector RipE1 of Ralstonia solanacearum by receptor Ptr1. Plant Physiology. 2024, doi: 10.1093/plphys/kiae514.

3. Shuangxi Zhang, Haijuan Li, Meixiang Zhang*, Yuyan An*. The MAP4 kinase NbM4K3 regulates immune responses in Nicotiana benthamiana. Phytopathology Research. 2024, doi: 10.1186/s42483-024-00265-6.

4. Peng Cao, Haotian Shi, Shuangxi Zhang, Jialan Chen, Rongbo Wang, Peiqing Liu, Yingfang Zhu*, Yuyan An*, Meixiang Zhang*. A robust high-throughput functional screening assay for pathogen effectors using the TMV-GFP vector. The Plant Journal. 2024, doi: 10.1111/tpj.16774.

5. Shuangxi Zhang, Xinlin Wei, Hejing Shen, Qinhu Wang, Yi Qiang, Langjun Cui, Hongxing Xu, Yuyan An*, Meixiang Zhang*. Simultaneously enhancing plant growth and immunity through the application of engineered Bacillus subtilis expressing a microbial pattern. Journal of Integrative Agriculture. 2024, doi: 10.1016/j.jia.2024.04.034.  

6. Yuyan An*, Meixiang Zhang*. Advances in understanding the plant-Ralstonia solanacearum interactions: Unraveling the dynamics, mechanisms, and implications for crop disease resistance. New Crops. 2024, doi: 10.1016/j.ncrops.2024.100014. 

7. Shuangxi Zhang, Xinlin Wei, Rongbo Wang, Hejing Shen, Hehuan You, Langjun Cui, Yi Qiang, Peiqing Liu, Meixiang Zhang*, Yuyan An*. Nicotinamide mononucleotide confers broad-spectrum disease resistance in plants. Journal of Integrative Agriculture. 2024, doi: 10.1016/j.jia.2024.04.027.

8. 张美祥*, 杨超*, 刘俊*. 植物病原菌效应子.科学通报. 2023, doi: 10.1360/TB-2023-0788.

9. Peng Cao, Jialan Chen, Ningning Li, Shuangxi Zhang, Rongbo Wang, Benjin Li, Peiqing Liu, Yuyan An*, Meixiang Zhang*. Seedling Petri-dish inoculation method: a robust, easy-to-use and reliable assay for studying plant-Ralstonia solanacearum interactions. Journal of Integrative Agriculture. 2023, 22:3709-3719.

10. Zuodong Wang, Xiaoxu Li, Xiaohui Yao, Jinbiao Ma, Kai Lu, Yuyan An, Zhimao Sun, Qian Wang, Miao Zhou, Lina Qin, Liyuan Zhang, Shenshen Zou, Lei Chen, Congfeng Song, Hansong Dong*, Meixiang Zhang*, Xiaochen Chen*. MYB44 regulates PTI by promoting the expression of EIN2 and MPK3/6 in Arabidopsis. Plant Communications. 2023, doi: 10.1016/j.xplc.2023.100628.

11. Kai Lu, Xiaochen Chen, Xiaohui Yao, Yuyan An, Xuan Wang, Lina Qin, Xiaoxu Li, Zuodong Wang, Shuo Liu, Zhimao Sun, Liyuan Zhang, Lei Chen, Baoyan Li, Baoyou Liu, Weiyang Wang, Xinhua Ding, Yonghua Yang, Meixiang Zhang*, Shenshen Zou*, Hansong Dong*. Phosphorylation of a wheat aquaporin at two sites enhances both plant growth and defense. Molecular Plant. 2022, 15:1772-1789.

12. Mou Zhang, Haotian Shi, Ningning Li, Nana Wei, Yan Tian, Jinfeng Peng, Xiaochen Chen, Liyuan Zhang, Meixiang Zhang^$, Hansong Dong^$,*. Aquaporin OsPIP2;2 links the H₂O₂ signal and a membrane-anchored transcription factor to promote plant defense. Plant Physiology, 2022, 188:2325-2341. (^$Senior author)

13. Xiaochen Chen, Jinbiao Ma, Xuan Wang, Kai Lu, Yan Liu, Liyuan Zhang, Jinfeng Peng, Lei Chen, Minkai Yang, Yang Li, Zaiquan Cheng, Suqin Xiao, Jinfeng Yu, Shenshen Zou, Yuancun Liang, Meixiang Zhang*, Yonghua Yang*, Xinhua Ding*, Hansong Dong*. Functional modulation of an aquaporin to intensify photosynthesis and abrogate bacterial virulence in rice. The Plant Journal, 2021, 108: 330-346.

14. Qi Li, Ji Wang, Tian Bai, Ming Zhang, Yuling Jia, Danyu Shen, Meixiang Zhang*, Daolong Dou*. A Phytophthora capsici effector suppresses plant immunity via interaction with EDS1. Molecular Plant Pathology, 2020, 21:502-511.

15. Qi Li, Yanyu Chen, Ji Wang, Fen Zou, Yuling Jia, Danyu Shen, Qimeng Zhang, Maofeng Jing, Daolong Dou, Meixiang Zhang*. A Phytophthora capsici virulence effector associates with NPR1 and suppresses plant immune responses. Phytopathology Research, 2019. 1:6.

16. Meixiang Zhang, Yi-Hsuan Chiang, Tania Y. Toruño, DongHyuk Lee, Miaomiao Ma, Xiangxiu Liang, Neeraj K. Lal, Mark Lemos, Yi-Ju Lu, Shisong Ma, Jun Liu, Brad Day, Savithramma P. Dinesh-Kumar, Katayoon Dehesh, Daolong Dou, Jian-Min Zhou, Gitta Coaker*. The SIK1 kinase ensures a robust extracellular ROS burst and anti-bacterial immunity by regulating BIK1 stability and RBOHD activation. Cell Host & Microbe, 2018, 24: 379-391.

17. Meixiang Zhang, Gitta Coaker*. Harnessing effector-triggered immunity for durable disease resistance. Phytopathology, 2017, 107: 912-919.

18. Meixiang Zhang, Qi Li, Tingli Liu, Li Liu, Danyu Shen, Ye Zhu, Peihan Liu, Jian-Min Zhou, Daolong Dou*. Two cytoplasmic effectors of Phytophthora sojae regulate plant cell death via interactions with plant catalases. Plant Physiology, 2015, 167: 164-175.

五、获奖情况

1. 2024中国星空体育研究生乡村振兴科技强农+创新大赛第四届科技作品竞赛全国总决赛三等奖（指导教师）

2. 2024中国星空体育研究生乡村振兴科技强农+创新大赛星空体育星空体育官方网站校内赛一等奖（指导教师）

3. 2024届星空体育星空体育官方网站本科生“优秀毕业论文”（指导教师）

4. 2020江苏省“青蓝工程”优秀青年骨干教师

5. 2020届本科生校级优秀毕业论文（设计） 二等奖（指导教师）

6. 2018公派留学回国人员绩效考核优秀

7. 2015届本科生校级优秀毕业论文（设计） 特等奖（指导教师）

8. 2014南京农业大学第十一届青年教师授课比赛优秀奖